Further Links Between Genetic and Viruses in Causing Multiple Sclerosis
Nov 17, 2020
Researchers uncovered a link between a DNA binding factor and reactions to lymphocytic chooriomeningitis virus in causing multiple sclerosis. This highlights how viral infections can underly a part of this deadly disease’s pathogenesis.
Nicolas Page, Bogna Klimek, Mathias De Roo, Karin Steinbach, Hadrien Soldati, Sylvain Lemeille, Ingrid Wagner, Mario Kreutzfeldt, Giovanni Di Liberto, Ilena Vincenti, Thomas Lingner, Gabriela Salinas, Wolfgang Brück, Mikael Simons, Rabih Murr, Jonathan Kaye, Dietmar Zehn, Daniel D. Pinschewer, Doron Merkler. Expression of the DNA-Binding Factor TOX Promotes the Encephalitogenic Potential of Microbe-Induced Autoreactive CD8 T Cells. Immunity, 2018; 48 (5): 937 DOI: 10.1016/j.immuni.2018.04.005
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